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[China]
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Serum amyloid A (SAA) is a kind of acute phase reaction protein secreted by the liver, which exists in the blood of healthy people. When viral or bacterial infection occurs, SAA begins to increase significantly in 3-6 hours, and increases hundreds or even thousands of times in acute state. The half-life of SAA is very short and will decrease rapidly during recovery. It is more sensitive than CRP, the combination of the two detection can better distinguish the type of infection, improve the diagnostic efficiency of virus infection.
| Detection range | sample size | Sample type | Test time |
| 5~200mg/L | 5μl | Whole blood / serum / plasma | 3min |
Dynamic monitoring
| Virus infection sensitivity index | SAA is more sensitive than CRP in the process of virus infection. Combined detection of CRP and SAA is helpful to identify early infectious diseases |
| Transplant rejection test indicators | Studies have found that SAA is one of the earliest indicators of rejection, and can be used as a sensitive marker for early monitoring of transplant rejection | |
| Monitoring indicators of tumor invasion and metastasis | SAA levels were significantly correlated with tumor activity, malignancy, invasion and metastasis, which can be used as one of the indicators of dynamic monitoring | |
| Predictors of cardiovascular events | Therefore, SAA can be used as an indicator for early prediction and prognosis of cardiovascular events | |
| Diagnostic indicators of AA amyloidosis | SAA is the precursor of AA and plays a key role in the
pathogenesis. The serum SAA of patients can be used as an
evaluation index of disease treatment and prognosis by keeping high
concentration for a long time |
| Index | CRP | SAA |
| Time of discovery | 1930 | 1976 |
| Clinical features | Increased bacterial infection 30% increase in viral infections | Virus infection is significantly increased Large increase in bacterial infections Infection cure has dropped significantly |
| Peak time | Rising period: 4-6 hours Platform period: 24-48 hours Half life: 18 hours | Rising period: 3-6 hours Platform period: 5-6 hours Half life: 50 minutes |
Laboratory, emergency, ICU, Pediatrics / neonatology, respiratory, surgery, hematology, rheumatology and immunology, oncology, Nephrology, etc.
