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High Speed Pharmaceutical Granulation Equipments Rapid Shear Wet Type Mixing

Jiangsu Hualian Yiming Machinery Co.,Ltd.
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Address: Fenghuang town, Zhangjiagang City,Jiangsu Province,China

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Jiangsu Hualian Yiming Machinery Co.,Ltd.

High Speed Pharmaceutical Granulation Equipments Rapid Shear Wet Type Mixing

Country/Region china
City & Province jiangsu
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Product Details

 

GHL Series HIGH SPEED MIXING GRANULATOR 

 

GHL high speed mixing granulator, high speed mixing granulator, high efficiency wet mixing granulator:
The mixed granulator is a new process of preparation used in the pharmaceutical industry of China in the 1980s.Compared with the traditional granulation technology, the advantages of mixed granulation are as follows :

(1) less adhesive dose is required for granulation, so the drying time is short.

(2) granulation can be made according to the existing formula without changing any process.

(3) the granulation time is only 7 to 10 minutes per batch.

(4) the particle boundary is clear, approximately spherical, uniform, small particle point, low density, so that when pressing the sheet, good liquidity, easy to fill the mold cavity, small pressure, sheet weight is stable, reduce laborDegrees.

(5) the particles are small, the particle boundary is destroyed during stamping, and it is easy to dissolve and diffuse.

(6) the surface of the film is smooth and fine.

(7) compared with extruded granules, the prepared granules are more loose and more compact than boiling granules.

The mixed granulator is the ideal equipment to meet the requirements of G, M and P during the eighth five-year plan period. The GHL high-speed mixing granulator designed and produced by our factory is the result of introducing the same kind of products and improving it. Foreign adhesive as part of the resin used in the organic solvent, and the pharmaceutical industry in our country most of the starch adhesive, we successively for 4 kinds of sulfonated ammonium, vitamin, antibiotic, compound class 10 drugs for granulating and tabletting, 10%, 13%, 15%, 18% used many different proportion of starch and different concentrations of organic solvent adhesive, the excellent performance of particles is created quality conforms to the standard.

Principle:

The powder raw material and adhesive in a cylinder are mixed fully at thebottom to turn into a humid soft material. Then it is crushed at a high speedand become uniform granules.

Application​:

GHL high speed mixing granulator is a high efficiency equipment that can mix different powder materials and granulate granule in one procedure. It is wide used for pharmaceutical industry, foodstuff industry and chemical industry, etc.
 

Technical characters:

· The machine adapts a practical horizontal cylinder structure, its structure is isreasonable, no deed corner.
. The driving shaft is equipped with inflatable seal. While washing, the air canbe replaced by water.
. Fluidized granulating processed is used and the final granules are quite roundwith high fluidity.
. Compared with traditional technique, this type of machine can reduce 25% ofadhesive and also shorten the drying time.
. For each batch of material, with 2 minutes' dry mixing and 1-4 minutes'granulating, the efficiency is 4-5 times higher than that of traditional technique.

·Dry mixing, wet mixing and granulating are finished inside the same sealedcontainer, which is in conformity with the requirements of "GMP" .

·The whole operation has strict safe and protective measure

Main Technical Parameter:  

TypeABC×DEF
503209501250×8009701650
15042010001350×80010501750
20050011001650×94014502050
25050011601650×94014002260
30055012001700×100014002310
40067013001860×110015502410
60075015002000×123017502610

 

NameType
 50150200250300400600
Capacity (L)50150200250300400600
Output (kg/batch)155080100130200280
Mixing speed (r.p.m200/400180/270180/270180/270140/220106/15580/120
Mixing power (kw)4/5.56.5/89/119/1113/1618.5/2222/30
Cutting speed (r.p.m)1500/30001500/30001500/30001500/30001500/30001500/30001500/3000
Cutting power (kw)1.3/1.82.4/34.5/5.54.5/5.54.5/5.56.5/89/11
Amount of compressed air(m/min)0.60.90.90.91.11.51.8
Wieght(kg)50080010001300180022002600

Scematic of installation:

 

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