BunnyTeeth Technology Inc. |
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BunnyMag cfDNA Isolation Kit (IVDR Certified) for Non-invasive Prenatal Screening
Cell-free DNA (cfDNA) is a fragment of cfDNA released from cells into the bloodstream that can carry biological information from tumors, pathogens and fetuses. The analysis of cfDNA provides key markers for diagnosis, detection and monitoring of disease progression. Currently, this technology has been widely used in the fields of tumor mutation detection, targeted drug guidance and prognosis, pathogen detection and non-invasive prenatal screening. BunnyMag cfDNA Isolation Kit (IVDR Certified) for Non-invasive Prenatal Screening uses magnetic beads with a unique separation function and a unique buffer system to extract high quality cfDNA from 0.5-4 mL of fresh or frozen plasma, serum, pleural fluid, ascites, cerebrospinal fluid and other cell-free body fluids.
Advantages
Figure 1. Efficient recovery of plasma cfDNA with different nucleic acid quantity
Addition of a known amount of exogenous DNA fragment to plasma, simulating 3 gradients of high and low nucleic acid content samples, and using 3 kits for simultaneous nucleic acid extraction. BunnyMag cfDNA Isolation Kit (IVDR Certified) for Non-invasive Prenatal Screening can recover cfDNA fragments from samples with different nucleic acid quantity efficiently, and the nucleic acid yield and reproducibility are better than similar products from competing companies.
Figure 2. Good linearity of cfDNA recovery efficiency in different volumes of plasma samples.
The cfDNA yields showed good linearity with the plasma sample volume, using BunnyMag cfDNA Isolation Kit (IVDR Certified) for Non-invasive Prenatal Screening for 0.5, 1, 2, and 4 mL plasma samples, respectively, and the peak patterns of the different volumes of extracted cfDNA were identical by Agilent 2100 DNA assay kit.
Main Composition: Lysis Binding Buffer, Washing Buffer 1 & 2, Proteinase K, Superparamagnetic beads
Storage Temperature: 10- 30 ℃ & 2-8 ℃
Shelf life: 12 months