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Address: Building G62, Phase 4 Plant, China Medical City, Taizhou City, Jiangsu Province
Contact name:Liu
Taizhou Zecen Biotech Co.,Ltd. |
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Vitamin nutrition bone metabolism index calibrator test kit for Clinical In Vitro Diagnostic analyzer
Bone metabolism markers can check calcium and phosphorus metabolism indicators, bone formation markers, bone resorption markers, etc., are the detection of metabolites produced by bone transformation, and can reflect the body's skeletal conditions, such as the rate of change in bone metabolism, osteoclasts and osteoblasts. Function, frequency and rate of bone turnover, etc., are helpful for the diagnosis of osteoporosis, osteomalacia and other diseases.
1. Calcium and phosphorus metabolism indicators: including parathyroid hormone, calcitonin, etc., by evaluating the body's calcium and phosphorus metabolism ratio, observing osteogenesis, and reducing the risk of rickets, rickets and other diseases;
2. Bone formation markers: including alkaline phosphatase, serum osteocalcin, type I procollagen propeptide, etc. Among them, alkaline phosphatase can evaluate osteoblast activity and bone formation, and serum osteocalcin can reflect bone formation It can also detect the efficacy of drugs used in osteoporosis, etc. And type I procollagen propeptide has more direct diagnostic significance for metabolic bone disease affecting collagen formation;
3. Bone resorption markers: including urinary calcium, urinary hydroxyproline, hydroxylysine glycosides, etc. Urinary calcium level detection can reflect the bone resorption status, but it is easily affected by diet, intestinal absorption function, etc., so it lacks specificity . Urinary hydroxyproline, hydroxylysine glycosides, etc. can reflect the state of collagen conversion in the whole body. In addition, indicators such as urinary deoxypyridinoline and urinary type I collagen carboxy-terminal peptide can also be checked.
CLIA calibrator of Bone Metabolism
| ITEM | 25-OH-Vit-D |
| BGP | |
| iPTH | |
| CT | |
| CTX | |
| PINP |
| Testing method | 1. Treat the calibrator as the sample to be tested, and place it in
the sample loading area of the instrument after mixing. Note that
when mixing Avoid air bubbles. 2. During the detection, the system detects the luminescence value (RLU value) of each calibration point, and calculates the luminescence value according to the nominal concentration and luminescence value. The calibration curve is automatically fitted by the instrument. In order to ensure the reliability of the calibration curve, the determination of the calibrator should be Make a double. 3. The generated calibration curve can be used for 28 days, but it should be re-calibrated after the following conditions: Change of batch number of supporting testing reagents; Change of batch number of luminescent substrate The measured value of the quality control product is not within the scope of quality control or the test results are inconsistent with the clinical situation; System for major repairs or maintenance. |
| Interpretation of test results | 1. For reasons such as methodology or antibody specificity, the
same sample was tested using reagents from different manufacturers. Testing with different reagents may give different test results, therefore, the results obtained by testing with different reagents should not be directly They are compared with each other in order to avoid false medical interpretations. 2. The quality control product can be used as a reference for the reliability of the current experimental results, and its measured value should be within the within the range allowed by the quality control sheet. Test results should be based on reference value ranges and other clinical factors and results Comprehensive judgment, when the test result is close to the upper limit or lower limit of the reference value range, it can be considered samples for confirmation testing. |
| Storage and expiration date | Stored at 2-8°C, the product is valid for 12 months. Reagents should be used within 1 month after opening, and stored at 2-8°C away from direct sunlight.
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