Wuhan Shuiyixing Pharmaceutical Chemical Co., Ltd. |
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Active Pharmaceutical Tamoxifen Citrate/ Nolvadex For Anti-tumor
and Anti-multidrug resistance
Quick Details
What is tamoxifen?
Tamoxifen blocks the actions of estrogen, a female hormone. Certain
types of breast cancer require estrogen to grow.
Tamoxifen is used to treat some types of breast cancer in men and
women. It is also used to lower a woman's chance of developing
breast cancer if she has a high risk (such as a family history of
breast cancer).
Tamoxifen may also be used for purposes not listed in this
medication guide.
Important information
Do not use tamoxifen if you are pregnant. It could harm the unborn
baby. Use a barrier form of birth control (such as a condom or
diaphragm with spermicide) while you are using this medication and
for at least 2 months after your treatment ends. You should not use
tamoxifen if you are allergic to it, if you have a history of blood
clots in your veins or your lungs, or if you are taking a blood
thinner such as warfarin (Coumadin).
Before using this medicine, tell your doctor if you have liver
disease, high triglycerides (a type of fat in the blood), a history
of cataract, or a history of stroke or blood clot. Also tell your
doctor if you if you are receiving chemotherapy or radiation
treatment.
If you are taking tamoxifen to reduce your risk of breast cancer,
you may need to take your first dose while you are having a
menstrual period. You may also need to have a pregnancy test before
you start taking this medicine, to make sure you are not pregnant.
Follow your doctor's instructions.
Taking tamoxifen may increase your risk of uterine cancer, stroke,
or a blood clot in the lung, which can be fatal. Talk with your
doctor about your specific risks in taking this medication.
To make sure this medication is not causing harmful effects, your
doctor may want you to have mammograms and to perform routine
breast self-exams on a regular basis. Your liver function may also
need to be tested. Visit your doctor regularly.
Tamoxifen Citrate Clinical application
1. Treatment of breast cancer.
2. Prevention of breast cancer.
3. Anti-tumor and anti-multidrug resistance.
By reducing membrane negotiability and enhancing rigidity of
inter-cell binding site, Tamoxifen citrate can reduce concentration
and activity of cancer metastasis promoter and various activating
enzymes, so as to inhibit or hinder growth and metastasis of cancer
cell. In addition, it can promote cells surrounding tumor focus to
secrete a negative growth factor-transforming growth factor TGF-G,
inhibiting multiply indefinitely of cancer cells; inhibiting
oxidative damage of DNA bases which is caused by hydrogen peroxide
generated from human neutrophils. So except for breast cancer, it
is good for treatment and prevention of other malignant neoplasms,
and is used for treatment of brain tumors, liver cancer, prostate
cancer, etc. In addition, Tamoxifen citrate can reduce release
effect of membrane P170 glycoprotein through reducing membrane
negotiability, improving intracellular effective concentration of
cytotoxic drug and reducing drug resistance.
4. Heart protection.
Use/Dosing
In terms of dosing for combating gynocomastia that has begun to
form, there is very little research. The limited research that does
exist does point to the fact that doses of 20-40mgs per day are
effective in treating the existing condition . However, anecdotally
users have reported sometimes using doses of 60-80mgs per day.
These doses may have more to do with users' impatience rather than
the need for higher doses, as no research indicates that such doses
are needed. It should be noted as well however that tamoxifen
citrate may have no effect on existing gynocomastia in some
individuals. Many users have indicated that the compound will only
help alleviate symptoms if the gynocomstia has not been apparent
for a long period of time. Of course, this is all subjective and
the effectiveness of the drug can only be determined on a trial and
error basis.
For use during post-cycle therapy users have anecdotally indicated
that doses ranging between 20 and 40mgs per day are average. These
doses have been shown to significantly raise levels of
testosterone, luteinizing hormone and follicle stimulating hormone.
Most users have reported when using tamoxifen citrate for their
post-cycle therapy they will administer the drug for a minimum of
three weeks. A maximum length has not necessarily been established
due to the few side effects associated with the compound. In this
case, this compound can be run for as long as wanted with little to
no concern being needed to be paid to potential side effects.
Our Competitive Advantages:
1,Rich experience.
Our company is a professional production leading factory in China
in pharmaceutical area of many years,our products have exported to
Germany, Spain, UK, USA, Australia, Middle East, and so on other
country, and we have got very good feedback from our customers, we
had Established long friendly relations of cooperation.
2,Great quality, purity and favourable.
Our company is a professional leading factory in China in
pharmaceutical area.Good quality is one of our secret
success.Double check for quality of every batch before delivering
to customer;
For appearance, we will take pictures of products in advance. We
offer the photos to you for your approval. Especially for lumpy
solid, we will check the appearance after melting to avoid visible
contaminations.
3.Package: Professional packing with professional materials and we
will give clients several packing way to choose after you contact
me through my email.
4,Competitive Prices : Low price with high qulity .As manufacturers
in China, we are allowed to bring you the highest quality
chemicals, ingredients, and additives at a superior price.
The more you buy the more competitive prices you will get.
5,Good after-sales service: making all efforts to meet customers'
need.Tell the package update ASAP, and will try best solve when
customer encountered various problems.