• Usually, the material must be weighed in the clean area to avoid changing its original purity. According to the biological activity of the material, its weighing should be completed in a completely independent area (independent fume hood, air flow form and dust capture). Grade D, grade C or grade A shall be selected according to the microbial contamination level of starting materials (e.g. < 100 CFU / g) or the requirements of process risk assessment.
• The sterile drug ingredients are weighed in the sterilized container under the condition of A-level (sterile operation platform), and then transferred to the liquid medicine container under the condition of A-level cleanliness. The background environment must meet the requirements of B-level cleanliness.
• Due to the falling off of particles (from solid materials) in the air and the possible influence of personnel, the handling of materials should comply with the operating procedures. When weighing sterile materials, the personnel's clothing must meet the requirements of class B cleanliness level, which also plays a role in personnel protection. In class D clean areas, dust masks / goggles should be worn when necessary for safety according to product characteristics.
• Weighing boxes is a kind of weighing device with exhaust air and negative pressure to the surrounding environment, which can effectively avoid cross pollution.

Characteristics & Features: