China Foodpharm Group Co., Ltd |
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TEST | STANDARD | RESULTS |
1.Aspect | An orange yellow or yellow, crystalline powder | Conforms |
2.Solubility | Insoluble in water, very soluble in methanol, chloroform, freely soluble in anhydrous alcohol and ethyl acetate. | Conforms |
3.E1%1cm | (458--486) | Conforms |
4.Melting Range | (52-55) | 53-54 |
5.Loss on drying | No more than 0.1% | 0.1% |
6.Residue on lgnition | No more than 0.1% | 0.04% |
7.Heavy metals | No more than 10ppm | Conforms |
8.Impurities (HPLC) | No more than 0.8% | 0.5% |
9.Residue Solvents (GC) | Hexane≤0.029% | Conforms |
Methanol≤0.3% | Conforms | |
Toluene≤0.089% | Conforms | |
10.Assay (HPLC) | No less than 98.5% on the dried basis | 99.1% |
Idebenone is a modified version of coenzyme Q10 (CoQ10), which is absolutely crucial for metabolic function. Without it, the electron respiratory chain breaks and cells cannot produce energy. It is also the only lipid-soluble antioxidant that is synthesized in our bodies. Natural levels of CoQ10 begin to decrease after age 30.
CoQ10 would be a perfect supplement for athletes that expend excessive energy or push the anaerobic envelope were it not for one important detail: under hypoxic conditions (like going anaerobic), CoQ10 becomes pro-oxidative and creates a powerful free radical that can damage DNA, mitochondria, and lipid membranes.
There is a synthetic variation of CoQ10 called ubiquinol, also known as idebenone. It has been formulated to have all the advantages of CoQ10 without the pro-oxidative drawback.