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Medicine Grade extract 98% naringin for capsule

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Complex Nature Biotechnology CO., LTD.

Medicine Grade extract 98% naringin for capsule

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Product Details

 

Medicine Grade extract 98% naringin for capsule
product details

 

1.Name: Naringin

2.CAS No.: 10236-47-2

3.Molecular formula: C27H32O14

4.Molecular weight: 580.54

5.Specification:98% 99%

6.Appearance: Little yellow fine powder

 

 

 

Product Description

 

Studies have shown that naringin interferes with enzymatic activity in the intestines and, thus, with the breakdown of certain drugs, resulting in higher blood levels of the drug. A number of drugs that are known to be affected by the naringin in grapefruit include calcium channel blockers, estrogen, sedatives, medications for high blood pressure, allergies, AIDS, and cholesterol-lowering drugs. Caffeine levels and effects of caffeine may also be extended by consuming grapefruit or grapefruit juice. While the effect of naringin on the metabolism of a drug can increase the drug's effectiveness, it can also result in dosages that are inadvertently too high. Therefore, it's best not to take any drugs with grapefruit juice unless the interaction with the drug is known. In addition, the effects of drinking grapefruit juice is cumulative, which means that if you drank a glass of grapefruit juice daily with your medication for a week, the drug interaction would be stronger at the end of the week than at the beginning Naringin can be used as an intermediate in the synthesis of many organic chemicals.
The best example is the sweeter neohesperidine dihydrochalcone.
Naringin is related to other flavanones known to have therapeutic action in influencing capillary permeability. For those pharmaceutical uses the better solubility of naringin in water is an advantage.

Product  Analysis

 

ItemSpecificationResultMethod
BasicProduct Information
Product namenaringin  
Part of the PlantfruitConform/
Country of OriginChinaConform/
Organoleptic Data
AppearanceFine powderConformNLS-QCS-1008
ColorLittle Yellow powderConformGB/T 5492-2008
Odor& TasteCharacteristicConformGB/T 5492-2008
Process Data
Solvent(s) UsedWater and ethyl alcoholConform/
Extract ration10:1Conform 
Content// 
Drying MethodSpray dryingConform/
ExcipientMaltodextrinConform/
Physical Characteristics
Particle Size (80 mesh)98.0%pass 80meshConformGB/T 5507-2008
Moisture<5.0%2.8%GB/T 14769-1993
Ash Content<4.0%1.4%AOAC 942.05, 18th
Solvent ResidueEur. PharmConformNLS-QCS-1007
Heavy Metals
Total Heavy Metals<10 ppmConformUSP <231>, method II
Arsenic<1.0 ppmConformAOAC 986.15, 18th
Lead<1.0 ppmConformAOAC 986.15, 18th
Mercury<0.5 ppmConformAOAC 971.21, 18th
Pesticide Residue
666<0.2ppmConformGB/T5009.19-1996
DDT<0.2ppmConformGB/T5009.19-1996
Microbiology
Total Plate Count<1,000cfu/g17cfu/gAOAC 990.12, 18th
Total Yeast & Mold<100cfu/g3cfu/gFDA (BAM) Chapter 18, 8th Ed.
E. ColiNegativeNegativeAOAC 997.11, 18th
SalmonellaNegativeNegativeFDA (BAM) Chapter 5, 8th Ed.

 

Product  Function

1. Cholesterol-lowering effect, help treating diabetes

2. Naringin (and grapefruit) can interfere with certain drugs including calcium channel blockers, sedatives, cholesterol lowering drugs, and estrogen

3. Naringin stimulates the effect of caffeine and could therefore increase its fat burning action.

 

 

 

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