Complex Nature Biotechnology CO., LTD. |
Medicine Grade extract 98% naringin for capsule
product details
1.Name: Naringin
2.CAS No.: 10236-47-2
3.Molecular formula: C27H32O14
4.Molecular weight: 580.54
5.Specification:98% 99%
6.Appearance: Little yellow fine powder
Product Description
Studies have shown that naringin interferes with enzymatic activity
in the intestines and, thus, with the breakdown of certain drugs,
resulting in higher blood levels of the drug. A number of drugs
that are known to be affected by the naringin in grapefruit include
calcium channel blockers, estrogen, sedatives, medications for high
blood pressure, allergies, AIDS, and cholesterol-lowering drugs.
Caffeine levels and effects of caffeine may also be extended by
consuming grapefruit or grapefruit juice. While the effect of
naringin on the metabolism of a drug can increase the drug's
effectiveness, it can also result in dosages that are inadvertently
too high. Therefore, it's best not to take any drugs with
grapefruit juice unless the interaction with the drug is known. In
addition, the effects of drinking grapefruit juice is cumulative,
which means that if you drank a glass of grapefruit juice daily
with your medication for a week, the drug interaction would be
stronger at the end of the week than at the beginning Naringin can
be used as an intermediate in the synthesis of many organic
chemicals.
The best example is the sweeter neohesperidine dihydrochalcone.
Naringin is related to other flavanones known to have therapeutic
action in influencing capillary permeability. For those
pharmaceutical uses the better solubility of naringin in water is
an advantage.
Product Analysis
Item | Specification | Result | Method |
BasicProduct Information | |||
Product name | naringin | ||
Part of the Plant | fruit | Conform | / |
Country of Origin | China | Conform | / |
Organoleptic Data | |||
Appearance | Fine powder | Conform | NLS-QCS-1008 |
Color | Little Yellow powder | Conform | GB/T 5492-2008 |
Odor& Taste | Characteristic | Conform | GB/T 5492-2008 |
Process Data | |||
Solvent(s) Used | Water and ethyl alcohol | Conform | / |
Extract ration | 10:1 | Conform | |
Content | / | / | |
Drying Method | Spray drying | Conform | / |
Excipient | Maltodextrin | Conform | / |
Physical Characteristics | |||
Particle Size (80 mesh) | 98.0%pass 80mesh | Conform | GB/T 5507-2008 |
Moisture | <5.0% | 2.8% | GB/T 14769-1993 |
Ash Content | <4.0% | 1.4% | AOAC 942.05, 18th |
Solvent Residue | Eur. Pharm | Conform | NLS-QCS-1007 |
Heavy Metals | |||
Total Heavy Metals | <10 ppm | Conform | USP <231>, method II |
Arsenic | <1.0 ppm | Conform | AOAC 986.15, 18th |
Lead | <1.0 ppm | Conform | AOAC 986.15, 18th |
Mercury | <0.5 ppm | Conform | AOAC 971.21, 18th |
Pesticide Residue | |||
666 | <0.2ppm | Conform | GB/T5009.19-1996 |
DDT | <0.2ppm | Conform | GB/T5009.19-1996 |
Microbiology | |||
Total Plate Count | <1,000cfu/g | 17cfu/g | AOAC 990.12, 18th |
Total Yeast & Mold | <100cfu/g | 3cfu/g | FDA (BAM) Chapter 18, 8th Ed. |
E. Coli | Negative | Negative | AOAC 997.11, 18th |
Salmonella | Negative | Negative | FDA (BAM) Chapter 5, 8th Ed. |
Product Function
1. Cholesterol-lowering effect, help treating diabetes
2. Naringin (and grapefruit) can interfere with certain drugs including calcium channel blockers, sedatives, cholesterol lowering drugs, and estrogen
3. Naringin stimulates the effect of caffeine and could therefore increase its fat burning action.