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Cervical Cancer Screening ICC Immunoassay Test Kit Staining Keypath P16

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Shenzhen Kisshealth Biotechnology Co., Ltd

Cervical Cancer Screening ICC Immunoassay Test Kit Staining Keypath P16

Country/Region	china
City & Province	shenzhen
Categories	Dyestuff Intermediates

Product Details

Intended Use

Keypath p16 Immunoassay Test Kit(ICC) is used for immunohistochemical staining on the basis of routine staining

(such asHE staining), and provides diagnostic auxiliary information for doctors.

Principle

Based on the principle of specific binding between immunological antigen and antibody, the antibody is combined with enzyme-labeled chromogenic system to form a complex, and enzyme substrate (chromogenic agent) is added to make it chromogenic to locate and characterize the antigen to be detected. The location of cell staining is nucleus/cytoplasm.

P16 is one of the cell cycle regulatory proteins, also known as "mitosis inhibitor". Its role is to competitively bind CDK4/6 with cyclin D, and stop

the process of cells from G1 to S, thus negatively regulating mitosis. In tumor cells, gene mutation or deletion often leads to the increase of p16

expression, but the cell cycle can not be regulated. This antibody is mainly used in tumor research.

Higher sensitivity