Active Member
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[China]
Address: 1401 Suite B, HuiXin IBC,No.1 Zhang Ba 1 Road, Hi-tech Development Zone, Xi\'an. China.
Contact name:Closer Meng
Xi 'an Green Spring Technology Co., Ltd |
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Certificate of Analysis
Product: Methyl hesperidin CAS-No.: 11013-97-1
Manufacturing Date: Nov.12th, 2017 Batch No.: RY171112
Expiry Date: Nov. 12th, 2019 Batch Size: 500 kg
| Nature of Test | Specifications | Test Results | |
| CHARACTERS | |||
| - Appearance | Orange yellow or light yellow crystalline powder; special foul odor; bitter taste; hygroscopic. | Light yellow crystalline powder; special foul odor; bitter taste; hygroscopic. | |
| - Solubility | Practically insoluble in ether, soluble in water, very slighty soluble in ethanol (96%) or acetone. | Conforms | |
| IDENTIFICATIONS | |||
| A. 10 mg + 10 ml of 60% ethanol + Mg | A violet red colour develops | Positive reaction | |
| B. 10 mg + 10 ml of 60% ethanol + FeCl3 | A brown red colour develops | Positive reaction | |
| TESTS | |||
| - Chalcone (TLC) | Should conform to the specification | Conforms | |
| - Heavy metals | ≤ 20 ppm | < 20 ppm | |
| - Loss on drying | ≤ 5.0 % | 3.7 % | |
| - Sulphated ash | ≤ 0.5 % | 0.31% | |
| ASSAY(by UV/Vis), on dried substance | ≥ 94.0% | 95.3 % | |
| RESIDUAL SOLVENTS | |||
| - Methanol | ≤ 3000 ppm | 273 ppm | |
| - Ethanol | ≤ 5000 ppm | 161 ppm | |
| MICROBIOLOGICAL TESTS | |||
| - Total aerobic microbial count | < 103 / g | < 102 / g | |
| - Total yeasts and moulds count | < 102 / g | < 10 / g | |
| - Escherichia coli | Absence in 1 g | Absence in 1 g | |
| CONCLUSION: THE TEST RESULTS CONFORM TO THE SPECIFICATION WS-10001 (HD-1386)-2003. | |||
| STORAGE: In an airtight container; protect from light. | |||
Application:
1. Applied in food field, various foods are use it as the materials;
2. Applied in pharmaceutical field, it is made into tablet or capsule, which is often used for eat
less and coughing much sputum;
3. Applied in cosmetic field, many sorts of orange peel oil can nourish the skin.
Functions:
1. Hesperidins has antioxidant, anti-inflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol lowering actions.
2. Hesperidins can inhibit following enzymes: Phospholipase A2,
lipoxygenase, HMG-CoA reductase and cyclo-oxygenase.
3. Hesperidins improve the health of capillaries by reducing the
capillary permeability.
4. Hesperidins are used to reduce hay fever and other allergic
conditions by inhibiting the release of histamine from mast cells.
The possible anti-cancer activity of hesperidins could be explained
by the inhibition of polyamine synthesis.
