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Anti - Inflammatory Pharmaceutical Raw Materials Miconazole Nitrate CAS 22832-87-7

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Anti - Inflammatory Pharmaceutical Raw Materials Miconazole Nitrate CAS 22832-87-7

Country/Region china
City & Province chongqing chongqing
Categories Electronics Chemicals

Product Details


Top Quality Anti-Inflammatory Pharmaceutical Raw Materials Miconazole Nitrate CAS 22832-87-7





Anti-inflammatory or antiinflammatory refers to the property of a substance or treatment that reduces inflammation or swelling. Anti-inflammatory drugs make up about half of analgesics, remedying pain by reducing inflammation as opposed to opioids, which affect the central nervous system.

Non-steroidal anti-inflammatory drugs (NSAIDs) alleviate pain by counteracting the cyclooxygenase (COX) enzyme. On its own, COX enzyme synthesizes prostaglandins, creating inflammation. In whole, the NSAIDs prevent the prostaglandins from ever being synthesized, reducing or eliminating the pain.

Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. The newer specific COX-inhibitors are not classified together with the traditional NSAIDs even though they presumably share the same mode of action.

On the other hand, there are analgesics that are commonly associated with anti-inflammatory drugs but that have no anti-inflammatory effects. An example is paracetamol (known as acetaminophen in the U.S). As opposed to NSAIDs, which reduce pain and inflammation by inhibiting COX enzymes, paracetamol has - as early as 2006 - been shown to block the reuptake of endocannabinoids, which only reduces pain, likely explaining why it has minimal effect on inflammation.



Quick Detail
Product NameMiconazole Nitrate
CharactersWhite powderOdorCharacteristic
Assay (%)≥ 99.00%Melting Point170-185°C
Molecular FormulaC18H15Cl4N3O4Molecular Weight479.14
Cas No.22832-87-7EINECS No.245-256-6
Main FunctionsAntifungal (topical).
ApplicationWidely used in pharmaceutical
PackageAluminum foil bag inside + carton box outside;1kg/bag+25kg/drum
Shelf Life36 months
StorageStore in sealed containers at cool & dry place. Keep away from light, moisture etc.




1. For serious infections caused by Candida species, including peritonitis, pneumonia and bladder infections. Miconazole nitrate can also be used for the treatment of the secondary infection due to the Gram-positive bacteria.

2. The area administration can be used treating chronic and extensive mucocutaneous candidiasis, vulvovaginitis candidiasis, tinea, ringworm, jork itch, athlete’s foot, tinea versicoeor and paronychomycosis due to various kinds of dermatophytes, yeast as well as other kinds of fungus.

3. Intravenous administration from it can be used for treating serious cryptococcosis, coccidioidomycosis and vice coccidioidomycosis.




Test ItemsSpecificationTest Results
AppearanceWhite or Almost white powderComplies
IdentificationIRSimilar to standardComplies
Appearance of SolutionThe solution is clear and not more intensely cloured than reference solutionsComplies
SolubilityVery slightly soluble in water; soluble in methanol ; slightly soluble in alcoholComplies
Angle of optical rotation-0.1o~+0.1oComplies
Related SubstancesEach Impurity≤0.25%0.18%
 Total Impurity≤0.5%0.25%
Melting Point163~167ºC164.5ºC
Loss on Drying≤0.5%0.32%
Residue on Ignition≤0.1%0.01%
Assay (on dry basis)98.0~102.0%99.38%



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