Jiangsu XIANDAO Drying Technology Co., Ltd. |
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LGX Series Solid Dosage production line
Product details
Production process flow for the newly-designed solid dosage production line
DESCRIPTION
Jiangsu XIANDAO Drying Sci-Tech Co., Ltd. specialize in granulator,
dryer and solid preparation equipment and so on. Combining with the
characteristics of domestic solid preparation production process,
our company designs the new type of solid dosage production line in
accordance with the characteristics of the domestic solid
preparation production.
At present, it is the new type online operation process which
effectively combines the wet granulation with wet
granule-processing, fluid bed drying, dry granule-processing,
material conveying, mixing and so on. It is applied for the
production of granules and the pre-production progress of tablet,
capsule, etc.
The process flow consists of high speed wet mixer granulator, wet
mill, fluid bed dryer, dry mill, vibrating sifter,mixer,vacuum
feeder, pharma lifter and so on .
It aims at improving productivity, reducing labor, guaranteeing
good sealing, decreasing the possible pollution links and achieve
dust-free during the production process.
Technical parameters:
Specs. | LGX-30 | LGX-60 | LGX-120 | LGX-150 | LGX-250 | LGX-300 | LGX-500 | Remarks | |
Capacity(kg/h) | 30 | 60 | 120 | 150 | 250 | 300 | 500 | ||
Model | LD moving hopper | LD-100 | LD-200 | LD-300 | LD-400 | LD-600 | LD-800 | LD-1200 | by user
|
Z KS vacuum feeder | Z KS-1 | Z KS-1 | Z KS-2 | Z KS-3 | Z KS-3 | Z KS-4 | Z KS-5 | ||
ZS vibration sieve | ZS-350 | ZS-515 | ZS-800 | ZS-800 | ZS-1000 | ZS-1000 | ZS-1200 | by user | |
Z KS vacuum feeder | Z KS-1 | Z KS-2 | Z KS-2 | Z KS-3 | Z KS-4 | Z KS-4 | Z KS-5 | by user | |
GHL series wet high speed mixing granulator | GHL-100 | GHL-200 | GHL-400 | GHL-500 | GHL-800 | GHL-1000 | GHL-1500 | necessary | |
GZL wet mill (/granule processor) | GZ L-80 | GZ L-180 | GZ L-250 | GZ L-300 | GZ L-350 | GZ L-350 | GZ L-450 | necessary | |
FG fluidizing dryer | FG-30 | FG-60 | FG-120 | FG-150 | FG-250 | FG-300 | FG-500 | necessary | |
Z KS vacuum feeder | Z KS-1 | Z KS-1 | Z KS-2 | Z KS-3 | Z KS-4 | Z KS-4 | Z KS-5 | by user
| |
NTF Series shopper Lifting-machine | NTF-100 | NTF-200 | NTF-300 | NTF-400 | NTF-500 | NTF-800 | NTF-1000 | ||
GZL dry mill (/granule processor) | GZ L-80 | GZ L-180 | GZ L-250 | GZ L-300 | GZ L-350 | GZ L-350 | GZ L-450 | by user | |
LD moving hopper | LD-100 | LD-200 | LD-300 | LD-400 | LD-600 | LD-800 | LD-1200 | by user |
Main scope of applications:
Pharmaceutical granulation and coating. Granulation: tablet
granules, granules for granules, granules for capsules. Coating:
protective layer of granules and pills, color preparation slow
release, film, enteric coating. Food granulation and coating.
Stir-fried sugar, coffee, cocoa powder, butter powder juice, amino
acids, seasonings, puffed food. Pesticides, pigments, dyes,
granulation. Dry powder, granule and block materials.
Notes:
Production Process Flow For The Newly-Designed Solid Dosage
Production Line
After weighing, the materials are inhaled into High speed Wet Mixing Granulator through vacuum feeder, at the same time,the adhesive from the Pressure liquid adding tank is atomized into the high speed mixing granulator by Pressure spray gun,then mixes with fine powder and become soft material. By the force of the cutting knife , the soft material become wet granule. through the wet mill , the wet granule will become uniform .the uniform wet granule enters the vertical fluid bed dryer to be dried by the vacuum negative pressure .the dried granule will discharge out by the vacuum discharger . the dried granule will be established the size through the dry mill . After that, the qualified and dried granule will enter the hopper mixer for general mixing by the vacuum discharger .then they can continue other processes.
After weighing, the materials are inhaled into High speed Wet Mixing Granulator through vacuum feeder, at the same time, the adhesive from the Pressure liquid adding tank is atomized into the high speed mixing granulator by Pressure spray gun, then mixes with fine powder and become soft material. By the force of the cutting knife , the soft material become wet granule . through the wet mill , the wet granule will become uniform .the uniform wet granule enters the vertical fluid bed dryer to be dried by the vacuum negative pressure .the dried granule will discharge out by the hopper lifter . the dried granule will be established the size through the dry mill . After that, the qualified and dried granule will enter the hopper mixer for general mixing by the vacuum discharger .then they can continue other processes.
After weighing, the materials are inhaled into High speed Wet Mixing Granulator through vacuum feeder, at the same time, the adhesive from the liquid adding tank is atomized into the high speed mixing granulator by Pressure spray gun, then mixes with fine powder and become soft material. By the force of the cutting knife , the soft material become wet granule . through the swaying granulator , the wet granule will become uniform .the uniform wet granule enters the dryer to dry by the vacuum negative pressure .the dried granule will discharge out by the vacuum discharger . The dried granule will be established the size through the dry mill. After that, the qualified dried granule will enter the hopper mixer for general mixing by the vacuum discharger .then they can continue other processes. (this process is suitable for processing the raw material with high viscosity.)
XIANDAO Provides You Advanced Technology Service
I. URS (User requirement standards)
Customers put requirements on the performance, technology, use and
service for products, which should be established in the contract
confirmed by both the manufacturer and buyer.
II. DQ (Design Qualification)
The user confirms whether the equipment chosen by the manufacturer
meets the standard requirement of "medicine production quality
management norms", product standards and other user demand.
III. FAT (Factory Acceptance Tests)
To ensure all indicators of the equipment are in accordance with
customer requirements, after completing the equipment but before
the shipment, the factory should do specific inspection on the
equipment's performance, technical data and configuration. After
the test, the customer should sign "Factory Testing Acceptance
Record".
IV. SAT (Site Acceptance Tests)
Manufacturers should take SAT at customer site base on the
requirements of the contract. if the SAT can be carried at the
manufacturer's site, after the customer finishes commissioning and
confirmation, the manufacturer should do package, and transport
according to the requirements of the contract.
V. IQ (Installation Qualification)
Check all kinds of system for the machine after installation as
well as the documentations relative to the machine .
VI. OQ (Operational Qualification)
All kinds of operation tests to ensure the device or equipment to
meet the setting requirements and documentation.
VII. PQ (Performance Qualification)
Trial production test to prove the equipment or systems related to
the equipment meet the setting requirements and documentation. The
Newly–Designed Solid Dosage Production Line.
The Advantage of The Solid Dosage Production Line
1. In traditional granulating and drying technology, each device is
set in separate rooms, so the material transfers between different
purification rooms, which can’t avoid the secondary pollution
phenomenon. While the newly-designed solid dosage production line
adopts the way of airtight transportation, ensuring the granulating
and drying to complete in the same purification room, which may
avoid the secondary pollution and make the granulating and drying
process more scientific and reasonable, besides, this reduces space
the equipment covers and make the process meet better with the GMP
requirements.
2. This machine takes full consideration of compatibility between
systems. Users can adjust corresponding equipment according to
customer's actual capacity and dosage forms to make the production
process achieve the optimum allocation, so as to ensure the
continuity and stability of the production.
3. The user can separately storage, collect and print the technical
data of the Wet granulation system and Fluidized drying system
through the HMI. The user can also control the parameter setting
and monitoring of several sets of equipment through a control
cabinet, besides, all the parameters can be set and modified, and
the user can set multilevel password through the corresponding
level. The main menu of the control system can reflect the working
state, data statistics in real time, and reflect the equipment
failure situations by fault self-diagnosis system and alarm
records, which makes the production process fully automatic, and
ensures the process stability.
4. The machine is able to fully show off the advantages of wet
granulator and Fluidized granulator. Besides, this combination can
guarantee high grain yield.
5. The vacuum feeder and pharma lifter have high automatic
production capability, which may take place traditional manual
operation, correspondingly reduce the labor intensity and dust
pollution.
6. We can configure cleaning-in-position in many different points
according to user requirements, which makes CIP more reliable.
Process descriptions
1. Vacuum feeding(Powder), add the adhesive to wet mixer granulator.
2. The wet mixer granulator complete the dry mixing, wet mixing, preparation granulating.
3. Wet mill for wet granulation(for western medicine), or by vibrate granulator(for Chinese medicine) .
4. Sucking the wet granules into the Vertical fluidizing dryer by the negative pressure effect.
5. Drying in the Vertical fluidizing dryer.
6. Transferring the dried granules into fixed tank by vacuum discharging way.
7. Dry granulating for the product in tank.
8. Discharging the finished dry granules into standard tank.
9. Transferring the standard tank into the mixing room by trolley.
10. Via the vacuum feeding, transfer the finished dry granules into the hopper mixer.
Remark: The above equipments can be in-line working, also can be used separately.