Pharmaceutical Industry SGS Clean In Place System

CIP for Pharmaceutical Process Plants

Product details

General descriptions

Cleaning-in-Place for Pharma Applications

Clean-in-Place (CIP) and Sterilize-in-Place (SIP) systems are designed to both automate essential cleaning and disinfection processes and remove the need for time-consuming disassembly and assembly work.

Process optimisation depends on efficient, effective cleaning. Clean-in-Place (CIP) systems can be incorporated into all the equipment produced by CZXD for the pharmaceutical industry, including both solid and liquid dosage formulation systems. Automating the cleaning process ensures repeatability, allows validation and minimizes downtime.

Compliant Cleaning Solutions and Cost Benefits

The most effective way to implement CIP technology is to design it into a process. Incorporating spray systems, tank cleaners, nozzles and seals to automate the cleaning process, we at XD consider every aspect of your system when applying CIP features, from inlet to discharge.

Automating the cleaning cycle essentially converts batch pharmaceutical processes into a continuous operation of production and cleaning cycles.

The advantages of CIP include:

Reduced cleaning cycle times

Optimized use of detergent and water

Eliminates manual cleaning.

At the heart of our CIP system is an advanced Wash Liquid Preparation Unit, which handles all filtering, preheating, mixing and pumping of water, detergents and demineralized water. It provides continuous monitoring and control of cleaning parameters, including flow rate, detergent concentration, temperature and wash time for full process validation.

WIP/CIP cleaning of XIANDAO

Our WIP/CIP cleaning systems supply your processing systems with all of the cleaning media needed for unlimited flexibility: from a standard version or individual cleaning modules for specific requirements to a central cleaning station for several systems. Everything is possible.

You have the choice between fully automatic CIP cleaning that does away with every manual cleaning step, or a system with semi-automatic WIP cleaning.

No matter whether you want to use your cleaning system with a XIANDAO system or a system from another manufacturer.

Our varied cleaning modules can be flexibly adapted to fit your needs. For instance, fresh water or circulation cleaning can be selected, as can dosing one or another cleaning agent.

Our smart modular design offers you the possibility to expand your basic model at any time with individual supplemental modules just as you need.

CIP/WIP System Skids

In today's pharmaceutical processes, integrated CIP solutions play a key role: from system skid selection to identifying the intended targets and required parameters. Variables such as temperature, velocity/pressure, chemical concentration and exposure time can all be controlled using a programmable CZXD CIP skid to deliver reliable, repeatable and verifiable results.

Our CIP/WIP system skids are designed, engineered, fabricated, automated and tested in-house. This vertically integrated approach allows for open communication between disciplines, enabling rapid response times to any variances that occur during the project lifecycle. A qualified Project/Process Engineer is assigned to your project to facilitate discussions regarding site-specific requirements, integration concerns and final FAT protocols.

In addition to defining and configuring your system skid, XD can further assist you to integrate CIP into your hygienic process and plant, ranging from conventional "make/break" manual flow panel methodology to the latest in matrix piping technology that utilizes mix-proof valve systems.

XD's CIP units are designed to guarantee successful cleaning and reduced waste generation. They can be integrated for the single use recovery of cleaning media, for single or multi-stream routes as well as for online and offline cleaning and sanitization. Our units provide functionality for CIP/SIP configurable recipes for water rinses, chemical washes, blow down and air drying, sanitation (heat or chemical), and flow, pressure, concentration and temperature controls.

Combined with our XD VARIVENT valves and spray jets ranges, our CIP systems provide a safe solution for product and cleaning efficiency. XD also offers wash systems for mobile tanks and IBCs.

CIP/SIP Solutions

Innovative CIP concepts of XD meet comprehensive high standards. Our experts guarantee product safety at every point of the process. Every upgrade is adapted to individual local conditions and customer requirements and leads to noticeable savings.

Individual consulting and customer-specific configurations aim at low investment costs, fast commissioning and short downtimes. Complete integration into the existing process control system ensures automatic and trouble-free cleaning and higher economic efficiency at the same time.

After preparation of the concept and order placement, project execution and successful commissioning by XD takes just a few weeks.

The modern CIP concepts of XD have already proven successful in many plants worldwide.

CIP for Pharmaceutical Process Plants

Process optimisation depends on efficient, effective cleaning. Clean-in-Place (CIP) systems can be incorporated into all the equipment produced by XD for the pharmaceutical industry, including fluid bed dryers, high-shear granulators and liquid dosage formulation systems. Automating the cleaning process ensures repeatability, allows validation and minimizes downtime.

Flow Chart (Only for refs.):

CIP System to Drying Chamber                                                         CIP System to IFD

      CIP System to the Cyclone Separator                                  CIP System to A Fluid-bed Dryer

        CIP cleaning position in the pipeline                                     Fully-automatic CIP Station