Best Price and High Quality Melanotan-II/Mt2 CAS No.: 121062-08-6
for Skin Tanning
Product name:Melanotan-II freeze-drying powder
Molecular Formula: C50H69N15O9
Molecular Weight: 1024.15
Packing(injection):10mg in 2cc vial,10mg/vial, 10 vials/kit
storaqge:protect sun damage and 2-8 degrees Celsius
Melanotan II Dosage:
Melanotan II is provided in freeze-dried (lyophilized) form and
reconstituted with bacteriostatic water. MT-2 may be injected
subcutaneously or intramuscularly with subcutaneous being the most
common and convenient. Melanotan II should be kept refrigerated at
all times, and should be discarded in 30 days after reconstitution.
Melanotan II is typically taken at a dose of 0.5-2mg per day with
0.5-1mg being enough for most individuals who use it for tanning
purposes. The same 0.5-1mg dosing is sufficient for erectile
Usage For Tanning:
Melanotan II is typically provided in vials containing 10 mg of
lyophilized (freeze-dried) powder. The vials are reconstituted with
a convenient amount of bacteriostatic or sterile water, added to
the vial by syringe. An example convenient amount of water is 2.5
mL. When this amount of water is used, the resulting solution
contains 4 mg of MT-II per mL. If for example wishing to take a
dose of 1 mg, a volume of 0.25 mL, or "25 IU" as marked on an
insulin syringe, would be taken by injection. Injection may be
subcutaneous, intramuscular, or intravenous, according to personal
Injection typically is only once per day, but where a person is
first trying the drug and judging tolerance, injection may be
divided into two smaller amounts per day.
Typical dosage range is 0.5 to 2.0 mg/day, with a preferred range
of 0.5 to 1.0 mg/day. However, it's best to first assess tolerance
with lower dosing of 0.25 mg at a time.
After reconstitution, a Melanotan II vial should preferably be
consumed entirely within 30 days. Prior to reconstitution, MT-II
should be stored in the refrigerator or freezer, but it's
acceptable for it to be shipped without refrigeration.
Melanotan II was first synthesized at the University of Arizona.
Researches there knew that onc of the best defenses against skin
cancer was melanin activated in the skin, a tan. They hypothesized
that an effective way to reduce skin cancer rates in people would
be to induce the body's natural pigmentary system to produce a
protective tan prior to UV exposure. The body's naturally occuring
hormone MSH causes melanogenesis, a process by which the skin's
pigment cells (melanocytes) produce the skin's pigment (melanin).
They tested to see if administering this endogenous hormone to the
body directly could be an effective method to cause sunless
tanning. What they found was that while it appeared to work,
natural MSH had too short a half life in the body to be practical
as a therapeutic drug. So they decided to find a more potent and
stable alternative, one that would be more practical.
After synthesizing and screening hundreds of molecules, the
researchers headed by Victor J. Hruby and Mac E. Hadley, found a
peptide, [Nle4, D-Phe7] MSH, that was approimately 1,000 times more
potent than the natural MSH. They dubbed this new peptide molecule,
"Melanotan" (later Melanotan-1, now know as afamelanotide). They
subsequently developed another analog,
Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they called
"Melanotan" Tanning Injections. The scientists hoped to use these
peptides to combat melanoma by stimulating the body's natural
pigmentary mechanism to create a tan without first needing exposure
to harmful levels of UV radiation. This in turn, they hypothesized,
could reduce the potential for skin damage that can eventually lead
to skin cancer.
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Use generally should be discontinued if MT-II, in the individual
case, causes problems with increased growth, number, or darkness of
Melanotan II's effect is fairly long-lasting. It can even be the
case that it takes a year or more for a cycle's effect to largely
disappear. Use of maintenance cycles can maintain effect
indefinitely. As a rule of thumb, maintenance typically requires
about 2 to 3 times as much MT-II per year as was needed for the
first cycle. This can be taken either as a total of 2 to 3 cycles
per year done in the same way as the initial cycle, or any more
frequent dosing pattern providing this total amount of MT-II per
How to use Melanotan II for prosexual effect
Where there is no physical erectile dysfunction and where at least
some degree of psychological libido exists, Melanotan II can
greatly increase the tendency to penile erection. The situation can
even become like the years of puberty, where scarcely even the
beginning of a sexual thought or even nothing at all (perhaps an
unconscious thought however) produces an erection. General physical
fatigue can become irrelevant. These effects will not occur for all
individuals, but do occur for many.
Prosexual usage requires injection at least about 4-6 hours prior
to desired effect. Duration of action can be about 6-12 hours after
onset of effect.
Needed dosage is typically about 1 mg, but for some even 0.5 mg can
be effective. As a guide, dosage should not exceed 2 mg.
Because of the associated effect in increasing tendency to tan,
frequency of MT-II use for this purpose is generally limited. If
wishing this effect frequently, a better choice is to use PT-141
(bremelanotide,) an MT-II derivative.
Melanotan II benefits
Lasting Tan:Even if dosage is stopped, a warm sun-kissed tan can
last for months at a time without any exposure to the
sun.Conversely, tans developed naturally fade in around a months
Flexibility of Use:Able to take a small loading dose with continued
dosing until desired skin pigmentation is achieved.Once achieved
only need to dose once every couple of weeks to maintain same
Reduced exposure to sunlight (UV rays):Melanotan still needs
exposure to sunlight to be effective.However it will allow the user
a significant reduction in time to develop desired tan .
Melanotan 1 compared with Melanotan 2
Melanotan 1 (also referred to as Afamelanotide) is a synthetic
peptide variant of a peptide hormone, called alpha-Melanocyte
stimulating hormone or MSH that is naturally produced in the body
and is responsible for stimulating melanogenesis, a peptide process
for pigmentation of the skin.Alpha-MSH activates certain
melanocortin receptors in the process of exerting its
effects.Indeed, MSH also exerts potent influence over lipid
metabolism, appetite, and sexual libido via these melanocortin
receptors.As a result, Melanotan-1 sunless skin tanning
effects.While Melanotan 2 and PT-141 have been studied at length as
a potential remedies for the treatment of sexual dysfunction,
Melanotan-1 has been researched extensively for use in protecting
against the harmful effects of ultraviolet radiation from sunlight
due to its melanogenesis-stimulating properties.
Both Melanotan-1 and Melanotan 2 are analogs of the peptide hormone
alpha-melanocyte stimulating hormone ( -MSH) that tend to induce
skin tanning.Unlike Melanotan 1, Melanotan 2 has been shown to have
aphrodisiac properties, the additional effect of increasing
libido.Melanotan-1 is a non selective agonist of the melanocortin
receptors (MC1R, MC3-5R).As an analogue of -MSH, its mechanism of
action is biomimicry of the natural mammalian tanning process.
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