Appearance: White to light yellow crystalline powder
Usage: Anti coagulation, anti allergy category of new drugs. Can be
used for urticaria, eczema, allergic contact dermatitis, skin
itching and other allergic reactions. Urticaria, eczema, allergic
and contact dermatitis, skin itching, rhinitis, bronchial asthma,
migraine. Can also be used in Cushing's disease and acromegaly
|Product Name||Cyproheptadine hydrochloride|
|Appearance||White crystal Powder||Odor||Characteristic|
|Purity||99%||Melting Point||165 °C (dec.)(lit.)|
|Molecular Weight||323.86||Molecular Formula||C21H22ClN|
|Cas No.||969-33-5||EINECS No.||213-535-1|
|Function||1. Cure urticaria, skin itch,allergic dermatitis|
2. Cure acromegaly
3. Cure coryza,hemicrania
4. Cure contact dermatitis
|Applications||Widely used in pharmaceutical|
|Packing||25kg/drum, inner double plastic bag or according to customers
|Shelf Life||2 years|
|Storage||Store in sealed containers at cool & dry place. Protect from
light, moisture and pest infestation.|
Cyproheptadine hydrochloride is a kind of pipecolic
antihistamines,it can compete with histamine released from the
organization for H1 receptor on effector cells , thereby it can
prevent the onset of an allergic reaction, and release
histamine-induced spasm and congestion effects, this product has a
strong H1 receptor antagonism, its anti-histamine effect is
stronger than chlorpheniramine, promethazine . There are mild to
moderate anti-serotonin effects and anticholinergic effects. In
addition, there is a stimulate appetite effect, and weight gains
after a certain time.
Clinically cyproheptadine hydrochloride is mainly used for acute
and chronic urticaria (especially it has a good effect on cold
urticaria ), papular urticaria, angioedema, atopic eczema, contact
dermatitis, food allergy, drug allergy, allergic rhinitis, hay
fever, allergic conjunctivitis, allergic to insect stings and
It has some therapeutic effect on bronchial asthma . It is
acceptable for the adjuvant treatment of Cushing's syndrome,
acromegaly. In addition,as an appetite enhancer,it is used for
neuropathic fear of food. There are reports about acanthosis
nigricans treatment, prevention of necrotizing pyoderma.
1. Cyproheptadine is used to treat allergic reactions (specifically
hay fever). It is also used to treat vasomotor mucosal edema,
including vasomotor rhinitis and edema of the throat.
2, It has shown effectiveness in the treatment of nightmares,
including those related to post-traumatic stress disorder.
3. It has been used in the management of moderate to severe cases
ofserotonin syndrome, a complex of symptoms associated with the use
ofserotonergic drugs, such as selective serotonin reuptake
inhibitorsand monoamine oxidase inhibitors), and in cases of high
levels of serotonin in the blood resulting from a
4. It can also be used as a preventive measure against migraine in
children and adolescents. In Australia this is the only indication
for which cyproheptadine is subsidised by the PBS.
5. It can relieve SSRI-induced sexual dysfunction and
drug-inducedhyperhidrosis (excessive sweating).
6. It is also used in the treatment of cyclical vomiting syndrome.
7. Use of the drug can stimulate the appetite and may lead to
weight gain, which is helpful for underweight people.
8. According to a small study, cyproheptadine hydrochloride has
been found to improve sleep, calmness, and mood and energy levels,
and to improve both negative and (sometimes even) positive
psychotic symptoms in a subgroup of chronic schizophrenics who did
not respond (either completely or sufficiently) to other therapies.
9. Cyproheptadine may improve akathisia in patients on
10. In clinical trials in which cyproheptadine was used as an
adjunct to antipsychotic treatment for patients with schizophrenia,
an improvement in negative symptoms was seen.
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