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Pharmaceutical Raw Materials Cyproheptadine Hydrochloride CAS 969-33-5

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Pharmaceutical Raw Materials Cyproheptadine Hydrochloride CAS 969-33-5

Country/Region china
City & Province zhuhai guangdong
Categories Spa Supplies

Product Details

Cyproheptadine hydrochloride


CAS: 969-33-5
Assay: 99%
Packing: 25kg/drum
MF: C21H22ClN
MW: 323.86
EINECS: 213-535-1
Appearance: White to light yellow crystalline powder
Usage: Anti coagulation, anti allergy category of new drugs. Can be used for urticaria, eczema, allergic contact dermatitis, skin itching and other allergic reactions. Urticaria, eczema, allergic and contact dermatitis, skin itching, rhinitis, bronchial asthma, migraine. Can also be used in Cushing's disease and acromegaly

Product NameCyproheptadine hydrochloride
AppearanceWhite crystal PowderOdorCharacteristic
Purity99%Melting Point165 °C (dec.)(lit.)
Molecular Weight323.86Molecular FormulaC21H22ClN
Cas No.969-33-5EINECS No.213-535-1
Function1. Cure urticaria, skin itch,allergic dermatitis
2. Cure acromegaly
3. Cure coryza,hemicrania
4. Cure contact dermatitis
ApplicationsWidely used in pharmaceutical
Packing25kg/drum, inner double plastic bag or according to customers requirement.
Shelf Life2 years
StorageStore in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.



Cyproheptadine hydrochloride is a kind of pipecolic antihistamines,it can compete with histamine released from the organization for H1 receptor on effector cells , thereby it can prevent the onset of an allergic reaction, and release histamine-induced spasm and congestion effects, this product has a strong H1 receptor antagonism, its anti-histamine effect is stronger than chlorpheniramine, promethazine . There are mild to moderate anti-serotonin effects and anticholinergic effects. In addition, there is a stimulate appetite effect, and weight gains after a certain time.


Clinically cyproheptadine hydrochloride is mainly used for acute and chronic urticaria (especially it has a good effect on cold urticaria ), papular urticaria, angioedema, atopic eczema, contact dermatitis, food allergy, drug allergy, allergic rhinitis, hay fever, allergic conjunctivitis, allergic to insect stings and migraine.

It has some therapeutic effect on bronchial asthma . It is acceptable for the adjuvant treatment of Cushing's syndrome, acromegaly. In addition,as an appetite enhancer,it is used for neuropathic fear of food. There are reports about acanthosis nigricans treatment, prevention of necrotizing pyoderma.


Medical Usage:

1. Cyproheptadine is used to treat allergic reactions (specifically hay fever). It is also used to treat vasomotor mucosal edema, including vasomotor rhinitis and edema of the throat.
2, It has shown effectiveness in the treatment of nightmares, including those related to post-traumatic stress disorder.
3. It has been used in the management of moderate to severe cases ofserotonin syndrome, a complex of symptoms associated with the use ofserotonergic drugs, such as selective serotonin reuptake inhibitorsand monoamine oxidase inhibitors), and in cases of high levels of serotonin in the blood resulting from a serotonin-producingcarcinoid tumor.
4. It can also be used as a preventive measure against migraine in children and adolescents. In Australia this is the only indication for which cyproheptadine is subsidised by the PBS.
5. It can relieve SSRI-induced sexual dysfunction and drug-inducedhyperhidrosis (excessive sweating).
6. It is also used in the treatment of cyclical vomiting syndrome.
7. Use of the drug can stimulate the appetite and may lead to weight gain, which is helpful for underweight people.
8. According to a small study, cyproheptadine hydrochloride has been found to improve sleep, calmness, and mood and energy levels, and to improve both negative and (sometimes even) positive psychotic symptoms in a subgroup of chronic schizophrenics who did not respond (either completely or sufficiently) to other therapies.
9. Cyproheptadine may improve akathisia in patients on antipsychotic medications.
10. In clinical trials in which cyproheptadine was used as an adjunct to antipsychotic treatment for patients with schizophrenia, an improvement in negative symptoms was seen.


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  • Package: Professional packing with professional materials.

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3. Package: Professional packing with professional materials
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