HSM25-1000 High-platform Pharmaceutical Granulation Equipments With In-line Mill HSM High Shear Mixer Wet Granulator

HSM25-1000 High-platform Pharmaceutical Granulation Equipments With In-line Mill HSM High Shear Mixer Wet Granulator

HSM High Shear Mixer

Description:

HSM High Shear Mixer is one of the main processing machineries in solid dosage mass production for mixing granules/powders and wet granulation. The machine is designed with a high operating platform for optimal process flow control and in-line milling system.

Common High Shear Mixer process time is about 12 mins. 

Wet granulation finished products are of good flowability, easy to dose/handle, low hygroscopic and compact structure. The granules with good solubility and high bulk density, granuler size 20~80 mesh, equivalent to 0.18~0.85 mm. 

It is also widely used in food, chemical industries for similar purposes.

Features:

High operating platform
In-line cone mill system
End-point process control
Closed transfer to fluid-bed
Traceability and repeatability
GMP compliant for pharmaceutical production

Options:

Jacketed bowl

WIP wash-in-place

Explosion-proof design

Automatic solution adding - according to solution viscosity 

Automatic raw materials feeding by vacuum
21 CFR part 11 compliant control system

Specifications:

 

Model	Machine Dimensions [mm]	Bowl Volume [L]	Capacity [kg]	Impeller Speed [rpm]	Cutter Speed [rpm]	Total Power [kW]	Machine Weight [T]
HSM25	1900x1320x2000	25	5~10	50~200	1000~2000	4.05	1
HSM50	2300x1790x2900	50	10~20	50~200	1000~2000	6.95	1.2
HSM75	2300x1750x3135	75	15~30	50~200	1000~2000	9.25	1.3
HSM100	2300x1790x3155	100	20~40	50~200	1000~2000	16.1	1.5
HSM150	2800x2440x3370	150	30~60	50~175	1000~2000	23.5	2.5
HSM200	2800x2440x3645	200	40~80	50~175	1000~2000	23.5	2.7
HSM300	2800x2455x3645	300	60~120	50~175	1000~2000	29	3.3
HSM400	2800x2490x3700	400	80~160	50~175	1000~2000	33.5	3.4
HSM500	2800x2860x3945	500	100~200	50~175	1000~2000	45	4.3
HSM600	2800x2840x3945	600	120~240	50~175	1000~2000	53.5	4.8
HSM800	2900x3140x4445	800	160~320	50~145	1000~2000	65.5	5.2
HSM1000	3100x3200x4600	1000	200~400	50~120	1000~2000	75.5	6

 

 

Product Pictures:

 

Two common methods for powder loading, by pharma lifter and by vacuum. 

          

 

Binder preparation tank and pressure binder spray tank. 

          

 

Final granule