Glass Bottle packing Pharmaceutical Transfusion Fluconazole
[Indications and Clinical use]: For candidiasis, cryptococcosis and
[Strength]: 100ml: 0.2g Fluconazole and 0.9g sodium chloride
Name: Pharmaceutical Transfusion Glass Bottle packing Fluconazole
Structural formula: C13H12F2N6O
Property: The product is colorless and pellucid liquid.
This product is a new member of triazole anti-fungal agents, it can
restrain the sterol combination of fungal efficiently. When the
drug is injected, it takes effect on various animal fungal
infections such as candidiasis infection and new type of
Absorption, distributing and elimination:
The plasma protein binding rate of Fluconazole was only 11-12%.
T1/2 is long, about 35.4 hours. The drug can permeate the body
fluid very well. Its concentrations in the saliva, sputum and
peritoneum are same with that in the plasma. Its concentration in
the cerebral spinal fluid is 80% of the concentration in the
plasma. Within 96 hours that patient is infused, the amount of
Fluconazole excreted unchanged in the urine is 80%.
Fluconazole is indicated for interfungal infection:
Cryptococcosis, including cryptococcosis meningitis and infections
of other parts (e. G. Pulmonary, cutaneous), normal hosts and
patient with AIDS, organ transplants or other cause of
immunosuppression may be treated.
Systemic candidiasis, patients with malignancy in intensive units,
receiving cytotoxic or immunosuppressive therapy, or with other
factors predisposing to candidal infection may be treated.
Administration and Dosage:
By drip phleboclysis, the rate of fluid administration should not
exceed 5mg/min. Because Fluconazole injection is the diluted
chloride sodium solution, the rate of fluid administration should
be taken into consideration when used for the patients who is
limited in the chloride or solution.
The treatment of crytococcosis meningitis and other parts infection
(such as lung, skin): Usually, the first dosage is 400 mg, the
dosages in the following days are 200-400 mg. The course of
treatment depends on fungal feedback. But for the cryptococcosis
meningitis, the period of treatment of that is 6-8 weeks at least.
The treatment of candidiasis blood poisoning and other candidiasis
General side effects: muzzy, headache, stomachache, spew and etc.
Glutamate pyruvatetransaminase ALT goes high slightly, haematoblast
The patients who have hypersusceptibility for Fluconazole and other
triazole drug are forbidden to use this product.
Pregnant women, suckle women and children are not appropriate to
use this product.
Patients who have tetter after taking the drug should be controlled
strictly. If the patients have the speckle, he should be stopped
For the patients who have to be given Fluconazole more than two
weeks or who have accept the treatment of Fluconazole with more
than general dose, or other medicines which have potential toxic
for the liver and maybe cause hepatic necrosis, they must be
examined by heptic function before the treatment. During the course
of treatment, heptic function should be re-examined every two
Interaction: When used with cumoric anhydride, pay attention to adjust the dose
of the anti-congelation; When used with sulfanilamides and
carbamide, pay attention to hypoglycemia reaction.
Packaging: 40 Glass bottles/carton
Storage: Avoid sunshine, store in cool and dry place.