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Freeze-drying (hereinafter referred to as lyophilization) is a
method in which an aqueous substance is first frozen into a solid
state, and then the water therein is sublimated from a solid state
into a gaseous state to remove water and preserve the substance.
In the field of biotechnology products, freeze-drying technology is
mainly used for the production of drugs such as serum, plasma,
vaccines, enzymes, antibiotics, hormones; biochemical inspection
drugs, immunology, and bacteriology; drugs; blood, bacteria,
arteries, bones Long-term preservation of skin, cornea, nerve
tissue and various organs.
* Many heat-sensitive substances do not degenerate or inactivate.
* When drying at low temperatures, some of the volatile components
in the material are lost.
* During the lyophilization process, the growth of microorganisms
and the action of enzymes cannot be carried out, so that the
original traits can be maintained.
* Since it is dried in a frozen state, the volume is almost
constant, and the original structure is maintained, and
concentration does not occur.
* The dried material is porous and spongy. After adding water, it
dissolves quickly and completely, and almost immediately restores
its original character.
* Since drying is carried out under a vacuum, there is very little
oxygen, so some easily oxidizable substances are protected.
* Drying can remove 95%~99% of water so that the products can be
preserved for a long time without deterioration.