White or white crystalline powder 99.4 Purity Pharmaceutical Grade
Raw Powder Domperidone CAS 57808-66-9 for Antiemetic
Domperidone Quick Details:
|MW: 425.91||MSDS: Avaiable|
|Category: API||Min order: 10grams|
|Quality standard: USP||Place of Origin:China|
|Appearance||Domperidone is a selective inhibitor of the peripheral D2DR. The
antidopaminergic effects of Domperidone have been correlated to
antiemetic and gastroprokinetic action.|
|Applications||Pharmaceutical raw materials , A peripheral D2DR inhibitor|
Domperidone is a peripheral, specific blocker of dopamine
receptors. It is administered orally, rectally, or intravenously.
Domperidone is given in order to relieve nausea and vomiting; to
increase the transit of food through the stomach (as a prokinetic
agent through increase in gastrointestinal peristalsis); and to
increase lactation (breast milk production) by release of
prolactin. It is also used in the scientific study of the way
dopamine (an important neurotransmitter) acts in the body.
There is some evidence that domperidone has antiemetic activity.
Domperidone is used, together with metoclopramide, cyclizine, and
5HT3 receptor antagonists (such as granisetron) in the treatment of
nausea and vomiting.
It can be used in patients with Parkinson's disease because, unlike
metoclopramide, domperidone does not cross the blood–brain barrier.
Domperidone has also been found effective in the treatment of
gastroparesis, a stomach motility condition, and for paediatric
gastroesophageal reflux (infant vomiting).
In Canada, the drug is indicated "for the symptomatic management of
upper gastrointestinal motility disorders associated with chronic
and subacute gastritis and diabetic gastroparesis." The drug may
also be used "to prevent gastrointestinal symptoms associated with
the use of dopamine agonist antiparkinsonian agents".
|Appearance||White to off white powder||White powder|
Practically insoluble in water, soluble in dimethylformamide,
slightly soluble in ethanol(96%) and in methanol
|Identification||A. M.P. 244~248℃||244.5~245.5℃|
|B. IR should comply||Confirms|
|C. TLC should comply||Confirms|
|D. It gives the reaction of non-nitrogen substituted barbiturates.||Confirms|
|Clarity of solution|
The solution is clear and not more intensely colored than
reference solution Y6
|Related substance||Total impurities≤0.5%||≤0.29%|
|Loss on drying||≤0.5%||0.07%|
|Conclusion: This product conforms to the EP7.0 detection.|
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(1) High Quality:Kafen Biotech is pharmaceuticals manufacturer with
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Pharmaceutical Raw Material
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|CAS:6700-34-1||Dextromethorphan (DXM or DM)|
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|14||CAS: NO||Testosterone Sustanon 250/100|
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|27||CAS:62-90-8||Nandrolone Phenypropionate (NPP)/durabolin|
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Order Process and Tips :
|Make an order||Please make clear what product and what quantity you need|
|Quote||Prices and Specifications details(COA) would be offered for you to
consider and confirm|
|Payment ways||T/T,Western Union, Money Gram and Bitcoin|
|Delivery ways||All Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.)|
|Shipping address||Provide your Valid and Correct destination address info(if possible
with post code, phone number).|
|Packing||Select best ways according to quantity and safety degree(Super
discreet, professional and experienced)|
|Leading time||Within 12 hours upon receipt of payment|
|Package pictures||Photos of parcel would be offered to tell apart the items|
|Tracking number||Offered once it is released|
|Shipping time||3-7 working days (Door-to-Door)|
|After-sale service||24/7 Online for any problems|
Why you choose us ? The 7 reasons are as below:
1. Rich experience:Our company is a professional production leading
factory in China in pharmaceutical area of 18 years.
2. Discreet package :The packing suits you best would be choosen to
cross customs safely. Or if you have your own ideal way, it could
be also taken into consideration .
3. Top quality:High quality guaranteed, once any problem is found,
the package would be reshipped for you .
4. Security Shipping:Shipping by professional forwarder Security
EMS/DHL/TNT/FedEx express door to door.
5. Fast delivery:we have stock, so we can delivery quickly once
payment is received.
6. Quality service:we will give you warm after-sale service,if any
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7. Competitive prices:A discount would be given when you make a
large order. VIP price for next orders.