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99.4 Purity Pharmaceutical Raw Materials Raw Powder Domperidone CAS 57808-66-9 for Antiemetic

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99.4 Purity Pharmaceutical Raw Materials Raw Powder Domperidone CAS 57808-66-9 for Antiemetic

Country/Region china
City & Province hangzhou zhejiang
Categories Amine

Product Details

White or white crystalline powder 99.4 Purity Pharmaceutical Grade Raw Powder Domperidone CAS 57808-66-9 for Antiemetic

 Domperidone Quick Details:

DomperidoneCAS 57808-66-9Brand:YC
MW: 425.91MSDS: Avaiable
MF:C22H24ClN5O2Sample: Avaiable
Category: APIMin order: 10grams
Quality standard: USPPlace of Origin:China
AppearanceDomperidone is a selective inhibitor of the peripheral D2DR. The antidopaminergic effects of Domperidone have been correlated to antiemetic and gastroprokinetic action.
ApplicationsPharmaceutical raw materials , A peripheral D2DR inhibitor

 

Product Description:

 

Domperidone is a peripheral, specific blocker of dopamine receptors. It is administered orally, rectally, or intravenously. Domperidone is given in order to relieve nausea and vomiting; to increase the transit of food through the stomach (as a prokinetic agent through increase in gastrointestinal peristalsis); and to increase lactation (breast milk production) by release of prolactin. It is also used in the scientific study of the way dopamine (an important neurotransmitter) acts in the body.

 

Product Application:

 

There is some evidence that domperidone has antiemetic activity. Domperidone is used, together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) in the treatment of nausea and vomiting.

 

It can be used in patients with Parkinson's disease because, unlike metoclopramide, domperidone does not cross the blood–brain barrier.

 

Domperidone has also been found effective in the treatment of gastroparesis, a stomach motility condition, and for paediatric gastroesophageal reflux (infant vomiting).

 

In Canada, the drug is indicated "for the symptomatic management of upper gastrointestinal motility disorders associated with chronic and subacute gastritis and diabetic gastroparesis." The drug may also be used "to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents".

 

Domperidone​ COA:

 

ItemsRequirementsResults
AppearanceWhite to off white powderWhite powder
Solubility

Practically insoluble in water, soluble in dimethylformamide,

slightly soluble in ethanol(96%) and in methanol

Confirms
IdentificationA. M.P. 244~248℃244.5~245.5℃
B. IR should complyConfirms
C. TLC should complyConfirms
D. It gives the reaction of non-nitrogen substituted barbiturates.Confirms
Clarity of solution

The solution is clear and not more intensely colored than

reference solution Y6

Confirms
Related substanceTotal impurities≤0.5%≤0.29%
Individual impurity≤0.25%≤0.18%
Loss on drying≤0.5%0.07%
Sulphated ash≤0.1%≤0.05%
Heavy metal≤20ppm<20ppm
Assay99.0%~101.0%99.49%
Conclusion: This product conforms to the EP7.0 detection.

 

 

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Pharmaceutical Raw Material

 

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Order Process and Tips :

Make an orderPlease make clear what product and what quantity you need
Mini Order10g
QuotePrices and Specifications details(COA) would be offered for you to consider and confirm
Payment waysT/T,Western Union, Money Gram and Bitcoin
Delivery waysAll Express Modes(EMS, DHL, TNT, FedEx, UPS, etc.)
Shipping addressProvide your Valid and Correct destination address info(if possible with post code, phone number).
PackingSelect best ways according to quantity and safety degree(Super discreet, professional and experienced)
Leading timeWithin 12 hours upon receipt of payment
Package picturesPhotos of parcel would be offered to tell apart the items
Tracking numberOffered once it is released
Shipping time3-7 working days (Door-to-Door)
After-sale service24/7 Online for any problems

 

Why you choose us ? The 7 reasons are as below:


1. Rich experience:Our company is a professional production leading factory in China in pharmaceutical area of 18 years.
2. Discreet package :The packing suits you best would be choosen to cross customs safely. Or if you have your own ideal way, it could be also taken into consideration .
3. Top quality:High quality guaranteed, once any problem is found, the package would be reshipped for you .
4. Security Shipping:Shipping by professional forwarder Security EMS/DHL/TNT/FedEx express door to door.
5. Fast delivery:we have stock, so we can delivery quickly once payment is received.
6. Quality service:we will give you warm after-sale service,if any question we will reply you within 24 hours.
7. Competitive prices:A discount would be given when you make a large order. VIP price for next orders.

 

 

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