Antidepression---St. John's Wort
Product name: St. John's Wort Extract
Specification: 0.3% Hypericins
Botanical Origin: Hypericum Perforatum L.
Part use: whole plant
St John’s wort is a perennial herb with a beautiful yellow flower.
Since ancient Greek times, the herb has been used to treat some
Today, people use St John’s wort extract to treat mild depression.
St. John's Wort Extract are among the most widely used
antideprssants in Germany. Hypericum, naturally in St. John's wort,
has antidepressant potential (Linde K etc 1996; Ernst E, 1995; De
Smet PA 1996).
St John's Wort extract displays many different classes of
antidepressants. The likely mechanism of action is the inhibition
of monoamine re-uptake(5-HT, NA and DA) with comparable potencies
to known atidepressants. Hypericum is also the only antidepressant
known that inhibits the uptake of all three monoamines with similar
potencies (PJ Nathan 1999).
Linde K, Ramirez G, Mulrow C. St John's Wort in depression—an
overview and meta-analysis of randomised clinical trials. BMJ 1996;
Ernst E. St John's Wort as an antidepressive therapy. Fortschr Med
1995; 113: 354-355
De Smet PA, Molen WA. St John's Wort as an antidepressant. BMJ
1996; 313: 153-157.
PJ Nathan. The experimental and clinical pharacology of St John's
Wort(Hypericum perforatum L.) Molecular Psychiatry(1999) 4,