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Pharmaceutical Grade Pain Reliever Tetracaine Powder CAS 94-24-6
Tetracaine (INN, also known as amethocaine; trade name Pontocaine.
Ametop and Dicaine) is a potent local anesthetic of the ester
group. It is mainly used topically in ophthalmology and as an
antipruritic, and it has been used in spinal anesthesia.
It is on the World Health Organization's List of Essential
Medicines, a list of the most important medication needed in a
basic health system.
|Test Items||Specification||Test Results|
|Appearance||Fine, white, crystalline, odorless powder||confirm|
|Identification||ABC in Pass||confirm|
|Solubility||Very soluble in water, soluble in Alcohol;|
insoluble in Ether and Benzene
|USP Reference standards||USP Tetracaine Hydrochloride RS.|
USP Endotoxin RS.
|Melting point||145~150 degree||146.0~147.5 degree|
|Chromatographic purity||In Pass||confirm|
|Related substance||Not more than the reference solution 0.05%||confirm|
|Residue on ignition||≤0.10%||0.05%|
|Loss on Drying||≤ 0.5%||0.19%|
|Conclusion||Confirms USP 32|
In biomedical research, tetracaine is used to alter the function of
calcium release channels (ryanodine receptors) that control the
release of calcium from intracellular stores. Tetracaine is an
allosteric blocker of channel function. At low concentrations,
tetracaine causes an initial inhibition of spontaneous calcium
release events, while at high concentrations, tetracaine blocks
Tetracaine is the T in Tac, a mixture of 5 to 12 per cent
tetracaine, 5M(per myriad), a half per mille (0.5‰), or .05 per
cent (1 part in 2000) , and 4 or 10 per cent hydrochloride used in
ear, nose & throat surgery and in the emergemcy department
where numbing of the surface is needed rapidly, especially when
children have been injured in the eye, ear, or other sensitive
Tetracaine is synthesized from 4-butylaminobenzoic acid. The ethyl
ester is formed through an acid-catalyzed esterification reaction.
Base-catalyzed transesterification is achieved by boiling the ethyl
ester of 4-butylaminobenzoic acid with excess
2-dimethylaminoethanol in the presence of a small amount of sodium
Small quantityAluminium bag, inside two level plastic bags(1KG or
Bulk quantity25kg/drum, inside two level plastic bags
Otherscan do your package or split small packages according to your
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