The TM analysis system is an accessory to UV-VIS spectrophotometers
(BioSpec-Mini, UV-1800, UV-2450/UV-2550 series, UV-3600), and is
comprised of an thermoelectrically temperature controlled micro
multi-cell holder employing a Peltier element and PC software
specially designed for the purpose. The Tm analysis system measures
the temperature at which the double strands which form nucleic
acids (DNA, RNA) and nucleic acid analogs (PNA, S-oligo nucleic
acid) separate (the melting temperature, Tm). It also makes
possible more detailed analysis (analysis of thermodynamic
parameters).
Features
- High throughput Tm measurement has been achieved through the
adoption of a 100ul 8 series micro multi-cell.
- All-in-one PC software is installed. By employing an easy to use
graphical interface, the whole sequence of actions from setting up
the measurement, to monitoring the measurement, Tm analysis, and
printing can be executed seamlessly. A multitude of functions has
been incorporated such as multiwavelength measurement, temperature
programming function, and continuous/ stepped scan support.
- Wide range, high precision temperature control
Wide range measurement from 0°C to 110°C is supported. To analyze
the Tm of samples below 37°C with a high degree of precision, data
at low temperatures below 4°C is essential